(A) localized scleroderma need to identify with these various diseases. 1 spot early damage for sizes shrink, or bluish skin color was, dimpled or uplift, surface wrinkling, touch not hard. 2 Atrophic lichen sclerosis lesions lavender shiny flat papules, sizes, often aggregated distribution, but do not integrate with each other, the surface of the hair follicle keratinocytes bolt, and sometimes blisters occur, the gradual emergence of skin atrophy.
(B) systemic sclerosis and following various diseases to be identified. 1 adult scleredema: multiple lesions began to develop upper body from the neck, swelling and stiffness in the deep dermis. No local pigmentation, atrophy and loss of hair and no performance, there are self-healing tendencies. 2 mixed connective tissue disease: Patients with mixed performance of systemic lupus erythematosus, scleroderma, dermatomyositis or polymyositis and other diseases, including Raynaud's phenomenon, face, hand non-pitting edema, showed a sausage-shaped swelling of the fingers , fever, non-destructive polyarthritis, muscle weakness or muscle pain and other symptoms. Leaching nuclear antigen (ENA) and RNP high titer antibody positive reaction was available. |