Skin ulcers are one of the treatment of scleroderma skin lesions common, especially systemic scleroderma. Scleroderma skin ulcers refer to local skin or mucosal necrosis, collapse of the limitations of off defect formation generally associated with more severe Raynaud's phenomenon.
Typical cutaneous manifestations of scleroderma can be presented swelling, hardening, shrinking three typical variations. Often appear in skin atrophy of skin ulcers, ulcers, mainly in the fingers finger, pointing the site of subcutaneous tissue thin joints, elbow, knee, etc. Early skin ulcers scleroderma may have swelling and pain in the typical performance, with exudation, the latter due to Jiubingtixu ulcers, ulcers are often difficult to heal, and easy to concurrent infection, severe ulcers may be deep to the bone surface. Western medicine that systemic scleroderma skin ulcers with circulation and immunity are closely related. Pathology showed endothelial swelling, intimal hyperplasia, fibrinoid necrosis, a lot of blood loss effect, resulting in reduction of skin blood perfusion, inadequate supply of nutrients, leading to local tissue ischemia, hypoxia, necrosis gradually formed. Now, Western medicine treatment of scleroderma to improve circulation, prevent infection based. |