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Mr. Guo Gang
Associate Chief Physician£¬Medical Postgraduate£¬Director of No.2 Department of Rheumatism ...[more] |
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| Clinical manifestations |
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| Contact Information |
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Add£ºNo.385 XinShiBei Road, Shijiazhuang, Hebei, China.
Code£º050091
Tel£º0311-83836460
Free Phone£º400-612-2156
Fax£º0311-83832249
E-mail£ºyuanban@yiling.org
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Getting There: Take the city bus 22
Yiling Hospital Road Station or take 48,58,368Under the new Stone Road. |
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Clinical manifestati
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Clinical manifestati |
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| What scleroderma skin lesions? |
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| Scleroderma patients with varying degrees of skin lesions, the light only fingers and facial skin tight, hard, often after a very long time to appear visceral damage, severe extensive skin thickening, involving the chest and abdomen and back. Typical skin lesions usually after three periods: skin lesions - like the first in the fingers and face appeared, was swelling edema, pressure up no depression (swelling of the period), some patients may have skin erythema, pruritus, patients often feel like the hand swelling like sausage, activities are not flexible. After the skin thickens, stiff fingers like being wrapped in leather, the skin can not be like normal people - like can easily be lifted (hardening period), his hands clenched fists can not, skin lesions may gradually to the arm, neck, upper chest , abdomen and back, spread legs rarely involved, the final skin atrophy, become smooth but seemed very thin, tightly attached to the bone surface of the skin, joint flexion contracture can not be straightened, but also skin ulcers, painful and difficult to heal. Hardened skin thinning, striae disappear, even the hair also fell off (contraction phase). Face making facial skin hardens striae disappear, when emotions all gone expression, mouth also not open. Other parts of the skin when the body can gradually softened, as clinically as normal, especially in the trunk and limbs of the skin. Diffuse scleroderma patient's skin hardens places often have pigmentation, skin darkening, some parts of the formation of white color dropout, so sprinkled on the skin like "salt and pepper" like. Skin also has a lot of red thread above, is the expansion of capillaries. CREST patients with subcutaneous calcification. The disease is usually chronic progress, some patients may have self-improvement. Use of prednisone in the swelling of the skin, such as glucocorticoids and effective, but can not block the course of the disease, the article reports abroad using penicillamine or colchicine can reduce skin lesions. Chinese medicine may also make the skin soft, but visceral damage of this disease requires corticosteroids and even merge immunosuppressive therapy. |
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