1 localized scleroderma (1) morphea: mostly occurs in the waist, back, followed by the limbs and face and neck, the performance of round, oval or irregularly shaped edematous plaques, beginning was pink or purple, after a few weeks or gradually expanded several months sclerosis, the color changes to yellow or ivory, local no sweat, hair loss, a few years later transformed into a white or light brown atrophic scars. Skin biopsy consistent with scleroderma change. (2) ribbon scleroderma: occurs in children and young people, more women than men, and limb lesions along the intercostal zonal distribution, for a single or a few lesions evolution with morphea. (3) guttate morphea: mainly in the neck, chest, shoulder, etc., about the size of green beans to the fifth coin, showing clustering of the linear array, its evolution seems morphea. 2 extremities with diffuse scleroderma scleroderma Extremities scleroderma have Raynaud's phenomenon, skin lesions developed from distal to proximal, torso, less visceral involvement, slow disease progression, prognosis is good; diffuse scleroderma lesions extend from the trunk to the remote, less Raynaud's phenomenon, visceral involvement and more. Severe illness, rapid disease progression, to the poor. (1) Raynaud's phenomenon: the first symptom in most patients, showed whitish ¡ú purple ¡ú red-phase change occurs, can be alleviated by the warmth after (toe) end of the cold or emotional fluctuations to mean; (2) Skin: disease process can be divided into edema, hardening and shrinking three. |