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Mr. Guo Gang
Associate Chief Physician£¬Medical Postgraduate£¬Director of No.2 Department of Rheumatism ...[more] |
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Scleroderma
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Scleroderma |
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| What systemic sclerosis autoantibodies are? |
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Systemic sclerosis as an autoimmune disease, there may be a variety of autoantibodies, including:
(1) anti-Scl-70 antibody diffuse systemic sclerosis iconic antibody positive rate of 40% to 60%;
(2) anti-centromere antibodies (ACA) is more common in the limitations of skin type, especially the landmark CREST syndrome antibody positive rate was 20% -70%; these two antibodies for the early diagnosis of systemic sclerosis are important significance.
(3) Other autoantibody positive rate from high to low, showing that the anti-nuclear antibody (ANA), rheumatoid factor (RF), anti-nucleolin antibody, anti-SSA antibody, anti-RNP antibodies, anti-SSB antibodies. A few patients may also appear anti-double stranded DNA antibodies, anti-cardiolipin antibodies. |
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