Cold hands and cold pain, a phenomenon known as Raynaud's phenomenon. Approximately 90% of scleroderma patients with Raynaud's phenomenon. This is due to intimal fibrosis caused by vascular obstruction, platelet activation, coagulation and fibrin deposition and the onset of the finger vascular spasm. Because of the finger tissue fibrosis patients with scleroderma and Raynaud's phenomenon occurs repeatedly, the patient finger subcutaneous (pulp) thin, hard, medically known as a hard fingers, fingertips black. Finger ischemia, ulceration, necrosis, causing fingers absorb shorter.

     In scleroderma patients, this phenomenon can be accompanied by skin changes and (or) other symptoms, some patients with Raynaud's phenomenon also occurs many years later, it happened the other manifestations of scleroderma. In addition to the fingers, toes, nose, tongue, lips and ear lobes and other parts of the extremities may also occur Raynaud's phenomenon. Raynaud's phenomenon can also occur in the body visceral arteries, causing lung, kidney, heart and brain and other vital organs artery disease, causing systemic visceral injury, dysfunction, and have serious consequences.